Zephyr is an item in TFT that removes an enemy champion from combat for the first 5 seconds of a round.

It lifts up the champion on the opponent's board that's in the mirrored position as the champion with Zephyr on your board. So if your champion with Zephyr is on your board, 2 squares from the left and bottom, then from your perspective, it'll affect the champion on the enemy board that's 2 squares from the right and top. If there are no champions on that spot, Zephyr lifts up the nearest champion to that spot.